HPLC-ESI-MS ANALYSIS OF SOME BIOACTIVE SUBSTANCES IN TWO YEMENI MEDICINAL PLANTS

Adel A. M. Saeed; Aisha Mohammed Ali; Taha Abubaker Fdhel

doi:10.47372/ejua-ba.2020.4.60

Authors

Adel A. M. Saeed Dept. of Chemistry, Faculty of Science, University of Aden, Aden, Yemen https://orcid.org/0000-0002-1154-2994
Aisha Mohammed Ali Dept. of Chemistry, Faculty of Education, University of Aden, Aden, Yemen
Taha Abubaker Fdhel Dept. of Chemistry, Faculty of Education, University of Aden, Aden, Yemen

DOI:

https://doi.org/10.47372/ejua-ba.2020.4.60

Keywords:

Medicinal plants, P. asirensis, P. amboinicus, Bioactive components, HPLC-ESI-MS.

Abstract

Plants have abundant bioactive components and play an important role in folk medicine, owing to their health beneﬁts in the treatment of many diseases, partially due to the secondary metabolite compositions. Nonetheless, detailed information on these substances is still limited. The recent work was aimed at investigating the bioactive substances of two Yemeni medicinal plants (i.e. Plectranthus asirensis and Plectranthus amboinicus) using reversed-phase high-performance liquid chromatography-electrospray ionization-mass spectrometry in a positive ionization mode. The proposed method provided a tentative identiﬁcation of several constituents such as alkaloids, fatty acids, steroids, and terpenoids. The obtained results highlight the importance of studied plants as a promising natural source of bioactive compounds.